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Displaying results 1 - 8 of 8
  • Syndromic Surveillance for a Large Respiratory Disease Outbreak by Legionella in the Netherlands

    Content Type: Abstract

    To evaluate the added value of a syndromic surveillance system in detecting a large severe respiratory disease outbreak with a point-source we used the Legionnaires' disease (LD) outbreak of 1999 in the Netherlands as a case-study. We… read more
    … Wilfrid van Pelt Ph.D., Arnold Dekkers Ph.D., Jan van de Kassteele Ph.D., Hans van Vliet M.D., Marion Koopmans … with a point-source. Using a syndromic approach we did a space-time analysis of hospital records to de- termine … surveillance. METHODS Hospital discharge diagnoses for all of 1999, (cover- age: 99%) were retrospectively analyzed …
  • Syndromic Surveillance with Death Data: Is Crude Mortality Data Suitable for Real Time Surveillance?

    Content Type: Abstract

    Crude mortality could be valuable for infectious disease surveillance if available in a complete and timely fashion. Syndromic surveillance with weekly deaths has been demonstrated to be useful in France. Such data can be of use… read more
    … Crude mortality could be valuable for infectious dis- ease surveillance if available in a complete and timely … and processed with a total 4 day delay. By 7 days almost all deaths are notified (median 92,8% IQR: 89,8-94,2) and … down to a 2 day delay (R2: 62%). Fig.1. Total deaths (top line) vs. deaths notified within 14, 7, 6, 5, 4, 3, 2, 1 …
  • Syndromic Surveillance for Detection of Increased Morbidity and Mortality by Influenza

    Content Type: Abstract

    To evaluate whether a rise or shift in severe morbidity and mortality by influenza can be detected with syndromic surveillance.
    … gen laboratory counts were used as predictive vari- ables. We assumed that if the actual syndrome counts … of influenza (or another common pathogen). REFERENCES [1] de Jong JC, Rimmelzwaan GF, Bartelds AI, Wilbrink B, … Geneeskd 2003; 147(40):1971-5. [2] Rimmelzwaan GF, de Jong JC, Bartelds AI, Wilbrink B, Fouchier RA, Osterhaus …
  • Respiratory Syndrome in the Netherlands in Relation to Pathogen Activity

    Content Type: Abstract

    Syndromic surveillance may be suited for detection of emerging respiratory disease elevations that could pass undiagnosed. The syndromes under surveillance should then retrospectively reflect known respiratory pathogen activity. To validate this for… read more
    … gen counts (-5 up to +5 weeks) as explanatory vari- ables. A forward stepwise regression approach was used, by … models with hierarchical time series models. RESULTS All respiratory pathogens and the residual values for …
  • Syndromic Surveillance for Localized Outbreaks of Lower-Respiratory Infections: Does it Work?

    Content Type: Abstract

    To evaluate whether syndromic surveillance can detect localized outbreaks of lower-respiratory infections (LRI'­s) with limited numbers of alarms in time.
    … Doornbos M.Sc., Nico J. D. Nagelkerke Ph.D., Wim van de Hoek, Hans van Vliet M.D., Marion P.G. Koopmans D.V.M. … OBJECTIVE To evaluate whether syndromic surveillance can de- tect localized outbreaks of lower-respiratory infec- … diagnoses by date of hospi- talization). We included all hospitalizations with any kind of lower-respiratory …
  • Greater Pathogenicity of Norovirus Strains in 2003? A Syndromic Approach

    Content Type: Abstract

    Although norovirus (NoV) is the most common cause of acute gastroenteritis (ewinter vomiting diseaseí), its contribution to mortality remains unknown and may be an unrecognized problem [1]. In Europe a genetic shift in circulating NoV strains was… read more
    … with an unusually high number of NoV outbreaks in all but one country participating in the European … with an unusually high number of NoV outbreaks in all but one country participating in the European … last somewhat longer than the ‘NoV peak’ period, perhaps due to the rotavirus and influenza season, which, both …
  • Validation of Data from Medical Registrations in The Netherlands for Syndromic Surveillance Use: Comparing Respiratory Syndromes with Laboratory Surveillance

    Content Type: Abstract

    Objective To study if syndromic surveillance would have an added value over existing surveillance systems, we retrospectively evaluated whether known trends in respiratory pathogens are reflected in medical registrations in the… read more
    … correlations. RESULTS Visually, seasonal variation in all three laboratory pathogens is reflected in the respiratory syndrome in all four medical registrations. The respiratory syndromes … RSV and influenza associated illness were reflected in all four registrations. In addition, an unexpected increase …
  • Understanding the Dynamics of Gastro-Intestinal Syndrome: General Practioner and Hospital Data vs Laboratory Surveillance

    Content Type: Abstract

    Objective Understanding the baseline dynamics of syndrome counts is essential for use in prospective syndromic surveillance. Therefore we studied to what extent the known seasonal dynamics of gastro-intestinal (GI… read more
    … values (up to 5 weeks backwards and forwards in time) of all GI pathogens as explanatory variables. For multivariate … was used, building each increment in the model by adding all possible lags of all pathogens and selecting the … summer/autumn) and hospital diagnoses (peaks in winter). Due to very high colinearity between several of the GI …