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Influenza

Description

The global H1N1 influenza A pandemic in 2009 heightened the need for automated disease surveillance capabilities. After an initial surge in confirmatory testing, clinicians

moved to diagnosis based on patient assessment for fever combined with cough or sore throat, the influenza-like indicators (ILI). Although some organizations used automated data capture or national systems with manual data entry (www.cdc.gov/flu/weekly/fluactivity.htm), there was not a turnkey national automated system in place to support syndromic surveillance for ILI among non-affiliated organizations. Semantic interoperability through standards utilization is widely expected to simplify large-scale data initiatives but is challenging with widely disparate uses of terminology.

 

Objective

This paper describes a national initiative connecting 850 non-affiliated healthcare provider organizations throughout the United States in order to provide situational awareness during the 2009–2010 H1N1 influenza A pandemic. We addressed the challenge of semantic variability between organizations through a centralized data-mapping approach.

Submitted by hparton on
Description

Seasonal influenza epidemics are responsible for over 200,000 hospitalizations in the United States per year, and 39,000 of them are in children. In the United States, the Advisory Committee on Immunization Practices guides immunization practices, including influenza vaccination, with recommendations revised on an annual basis. For the 2006–2007 flu season, the Advisory Committee on Immunization Practices recommendations for influenza vaccination began including healthy children aged 24–59 months (two to four years), a shift that added 10.6 million children to the target group.

Canada has a parallel federal organization, the National Advisory Committee on Immunization, which is responsible for guiding the use of vaccines. Recommendations made by the National Advisory Committee on Immunization and the Advisory Committee on Immunization Practices around seasonal influenza vaccination was concordant until the 2006–2007 season. Starting in the 2010–2011 season, the National Advisory Committee on Immunization has further expanded its recommendations to additional pediatric age groups by including two- to four-year-olds for targeted seasonal influenza vaccination.

We took advantage of this divergence in policy between two neighboring countries with similar annual seasonal influenza epidemics to try to understand the effects of the

policy change in the United States to expand influenza vaccination coverage to other pediatric populations.

 

Objective

The objective of this study is to estimate the effect of expanding recommendations for routine seasonal influenza vaccination to include 24–59-month-old children.

Submitted by hparton on
Description

The Centers for Disease Control and Prevention's (CDC) Emerging Infections Program (EIP) monitors and studies many infectious diseases, including influenza. In 10 states in the US, information is collected for hospitalized patients with laboratory-confirmed influenza. Data are extracted manually by EIP personnel at each site, stripped of personal identifiers and sent to the CDC. The anonymized data are received and reviewed for consistency at the CDC before they are incorporated into further analyses. This includes identifying errors, which are used for classification.

 

Objective

Introducing data quality checks can be used to generate feedback that remediates and/or reduces error generation at the source. In this report, we introduce a classification of errors generated as part of the data collection process for the EIP’s Influenza Hospitalization Surveillance Project at the CDC. We also describe a set of mechanisms intended to minimize and correct these errors via feedback, with the collection sites.

Submitted by hparton on
Description

Predictionmarkets have been successfully used to forecast future events in other fields. We adapted this method to provide estimates of the likelihood of H5N1 influenza related events.

 

Objective

The purpose of this study is to compare the results of an H5N1 influenza prediction market model with a standard statistical model.

Submitted by hparton on
Description

Reporting notifiable conditions to public health authorities by health-care providers and laboratories is fundamental to the prevention, control, and monitoring of population-based disease. To successfully develop community centered health, public health strives to understand and to manage the diseases in its community. Public health surveillance systems provide the mechanisms for public health professionals to ascertain the true disease burden of the population in their community. The information

necessary to determine the disease burden is primarily found in the data generated during clinical care processes.

 

Objective

This poster will present a predictive model to describe the actual number of confirmed cases for an outbreak (H1N1) based on the current number of confirmed cases reported to public health. The model describes the methods used to calculate the number of cases expected in a community based on the lag time in the diagnosis and reporting of these cases to public health departments.

Submitted by hparton on
Description

The South Carolina Aberration Alerting Network (SCAAN) is a collaborative network of syndromic systems within South Carolina. Currently, SCAAN contains the following data sources: SC Hospital Emergency Department chief-complaint data, Poison Control Center call data, Over-the-Counter pharmaceutical sales surveillance, and CDC’s BioSense biosurveillance system. The Influenza-like Illness Network (ILINet) is a collaboration between the Centers for Disease Control, state health departments and health care providers. ILINet is one of several components of SC’s influenza surveillance.

 

Objective

This paper compares the SCAAN hospital-based fever–flu syndrome category with the South Carolina Outpatient ILINet provider surveillance system. This is the first comparison of South Carolina’s syndromic surveillance SCAAN data with ILINet data since SCAAN’s deployment.

Submitted by hparton on
Description

Under-ascertainment of severe outcomes of influenza infections in administrative databases has long been recognised. After reviewing registered deaths following an influenza epidemic in 1847, William Farr, of the Registrar-General's Office, London, England, commented: ''the epidemic carried off more than 5,000 souls over and above the mortality of the season, the deaths referred to that cause [influenza] are only 1,157"[1]. Even today, studies of the population epidemiology, burden and cost of influenza frequently assume that influenza's impact on severe health outcomes reaches far beyond the number of influenza cases counted in routine clinical and administrative databases. There is little current evidence to justify the assumption that influenza is poorly identified in health databases. Using population based record linkage, we evaluated whether the assumption remains justified with modern improvements in diagnostic medicine and information systems.

Objective

To estimate the degree to which illness due to influenza is under-ascertained in administrative databases, to determine factors associated with influenza being coded or certified as a cause of death, and to estimate the proportion of coded influenza or certified influenza deaths that is laboratory confirmed.

Submitted by elamb on
Description

Pandemic 2009 H1N1 influenza and recent H7N9 influenza outbreaks made the public aware of the threat of influenza infection. In fact, annual influenza epidemic caused heavy disease burden and high economic loss around the world [1, 2]. Although the virological surveillance provided the high sensitivity and specificity for testing results, the timeliness and the cost of the test were not feasible for extensive public health surveillance. In addition, traditional sentinel physician surveillance also encountered many challenges such as the representativeness and reporting bias. The seamless surveillance system without extra labor reporting would be the ideal approach. Taiwan had as high as 99% of health insurance coverage. The real-time monitoring of the ILI clinical visits in the communities could reflect the severity of influenza epidemics. In this study, we used an innovative two-stage approach for detecting aberrations during 2009 pandemic influenza in Taiwan.

Objective

This study proposed a two-stage approach for early detection of aberrations of influenza-like illness (ILI) using the small-area based claim data of outpatient and emergency room visit.

Submitted by elamb on
Description

The Influenza Division (ID) in the Centers for Disease Control and Prevention (CDC) maintains the WHO/NREVSS surveillance system, a network of laboratories in the U.S. that report influenza testing results. This system has seen many changes during the past 40 years, especially since the 2009 H1N1 pandemic. This was due in large part to increased adoption of HL7 messaging via PHLIP. PHLIP data is detailed, standardized influenza testing information, reported in near real-time. The data received through this and other report methods is published online in national and regional aggregate form in FluView, a weekly surveillance report prepared by CDC.

Objective

Describe the changes to the World Health Organization/National Respiratory and Enteric Virus Surveillance System (WHO/NREVSS) influenza surveillance system over time, with a focus on the Public Health Laboratory Interoperability Project (PHLIP) and how it has influenced the system

Submitted by elamb on