The National Notifiable Disease Surveillance System (NNDSS) comprises many activities including collaborations, processes, standards, and systems which support gathering data from US states and territories. As part of NNDSS, the National Electronic Disease Surveillance System (NEDSS) provides the standards, tools, and resources to support reporting public health jurisdictions (jurisdictions). The NEDSS Base System (NBS) is a CDC-developed, software application available to jurisdictions to collect, manage, analyze and report national notifiable disease (NND) data.