Disease Transmission

Anthrax is an acute especially dangerous infectious disease of animals and humans. Bacillus anthracis is a potential bioterrorism tool. In Ukraine, there are favorable natural conditions for the spread of anthrax. There are 13.5 thousand of constantly anthrax-troubled points. Anthrax epidemic situation in Ukraine could be characterized as unstable. Because of the continuing reform of Ukrainian human health entities, the State Sanitary Epidemiological Service (SSES) has lost its control functions and is remaining in an uncertain state, which increases possible risks.

Since Cryptosporidium can be transmitted by ingestion of infected food animals and poorly treated water and by direct contact it is possible for infection to occur through ingestion of under cooked frogs and through handling and processing of infected frogs. In Burkina Faso frogs caught are sold to market-women who treat the frogs by emptying their bowels and frying in oil before selling them, this is not always the case for the Nigerian frog markets where frogs are sometimes smoked or dried without necessarily been fried, before consumption . This may pose a health risk for transmission of cryptosporidiosis from infected frogs.

Objective

To evaluate the occurrence of Cryptosporidium species in edible frogs (Ranaspp) sold at the Hanwa frog market Zaria, Kaduna State,Nigeria

Clostridium difficile (CD), a gram-negative, anaerobic, sporeforming bacterium causes symptoms ranging from mild to severe diarrhea and may result in death. Approximately 75% of CDI cases have symptom onset outside of health care settings. Annual US costs of treatment and infection containment have surpassed $4.8 billion. Risk factors for CDI include recent broad-spectrum antibiotic exposure, advanced age, severe underlying morbidities, immunocompromised status, long-term hospital stays, and residence in long-term-care facilities. Nationally, CO-CA cases have increased from 2.8/100,000 person in 1993 to 14.9/100,000 person in 2005.

Objective

Identify population-based Clostridium difficile infection (CDI) incidence stratified by Health Care Facility Onset (HCFO), Community Onset-Healthcare Facility Associated (CO-HCFA), and Community Onset-Community Associated (CO-CA) CDI in Denver County from 2011 - 2013 and describe demographic, health care facility exposure, and medication use risk factors.

MERS-CoV was discovered in 2012 in the Middle East and human cases around the world have been carefully reported by the WHO. MERS-CoV virus is a novel betacoronavirus closely related to a virus (NeoCov) hosted by a bat, Neoromicia capensis. MERS-CoV infects humans and camels. In 2015, MERS-CoV spread from the Middle East to South Korea which sustained an outbreak. Thus, it is clear that the virus can spread among humans in areas in which camels are not husbanded.

Objective

Here we use novel methods of phylogenetic transmission graph analysis to reconstruct the geographic spread of MERS-CoV. We compare these results to those derived from text mining and visualization of the World Health Organization’s (WHO) Disease Outbreak News.

Local transmission of Zika virus has been confirmed in 67 countries worldwide and in 46 countries or territories in the Americas. On February 1, 2016 the World Health Organization declared a Public Health Emergency of International Concern due to the increase in microcephaly cases and other neurological disorders reported in Brazil. Several countries issued travel warnings for pregnant women travelling to Zika-affected countries with Brazil, Colombia, Ecuador, and El Salvador advising against pregnancy. The risk of local transmission in unaffected regions is unknown but potentially significant where competent Zika vectors are present and also given the additional complexities of sexual transmission and population mobility. Despite the rapid spread of Zika virus across the Americas and global concerns regarding its effects on fetuses, little is known about the pattern of spread. Knowledge of the direction and the speed of movement of disease is invaluable for public health response planning, including the timing and placement of interventions.

Objective

To estimate the velocity of Zika virus disease spread in Brazil using data on confirmed Zika virus disease cases at the municipal-level.

Rabies is endemic in Tanzania and has circulated on Pemba Island since the late 1990s. In 2010, an elimination programme was initiated in Southern Tanzania to demonstrate that human rabies deaths can be eliminated through mass dog vaccinations. We used active surveillance approaches to investigate the dynamics of rabies across the area where this programme was implemented.

Objective

Using active surveillance approaches to investigate the transmission dynamics of rabies on Pemba Island and across Southern Tanzania, whilst a large-scale dog vaccination program was underway, to gain a greater understanding of the dynamics of infection as the disease is driven towards elimination.

Aquatic birds are the main reservoirs of influenza viruses, however, pigs represent an essential host in virus ecology as they are susceptible to both avian and human influenza viruses. Circulating zoonotic influenza (A/H7N9, A/H5N1, and A/H3N2v) viruses could mutate into forms easily transmissible from human-to-human and become a public health concern. Georgia is located along routes used by migrating birds where different species of aquatic birds are found. In 2006, highly pathogenic influenza virus A/H5N1 was detected in two wild swans in Adjara (western Georgia). Moreover, in the frame of wild bird surveillance, various subtypes of influenza A viruses were detected in mallard and gulls in Georgia (Lewis, 2013). Thus domestic animals in Georgia have a potential chance to contract influenza viruses from wild birds. 

Objective

The purpose of this study was to identify zoonotic influenza viruses in swine and poultry populations in Georgia and to define their pandemic potential. 

Annually sporadic cases of tularemia in humans are registered in Ukraine and new enzootic areas are found. Monitoring of tularemia natural foci is important given the potential significant financial losses in case of tularemia outbreaks and taken into account that this pathogen can be used as a bioterrorist agent.

Objective

Study the activity of natural foci of tularemia and identify the main types of reservoirs and vectors of Francisella tularensis.