Clostridium difficile (CD), a gram-negative, anaerobic, sporeforming bacterium causes symptoms ranging from mild to severe diarrhea and may result in death. Approximately 75% of CDI cases have symptom onset outside of health care settings. Annual US costs of treatment and infection containment have surpassed $4.8 billion. Risk factors for CDI include recent broad-spectrum antibiotic exposure, advanced age, severe underlying morbidities, immunocompromised status, long-term hospital stays, and residence in long-term-care facilities. Nationally, CO-CA cases have increased from 2.8/100,000 person in 1993 to 14.9/100,000 person in 2005.
Objective
Identify population-based Clostridium difficile infection (CDI) incidence stratified by Health Care Facility Onset (HCFO), Community Onset-Healthcare Facility Associated (CO-HCFA), and Community Onset-Community Associated (CO-CA) CDI in Denver County from 2011 - 2013 and describe demographic, health care facility exposure, and medication use risk factors.