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Real-time Adaptive Monitoring of Vital Signs for Clinical Alarm Preemption

Description

Cardiovascular event prediction has long been of interest in the practice of intensive care. It has been approached using signal-processing of vital signs [1-4], including the use of graphical models [3,4]. Our approach is novel in making data segmentation as well as hidden state segmentation an unsupervised process, and in simultaneously tracking evolution of multiple vital signs. The proposed models are adaptable to the individual patient's vitals online and in real time, without requiring patient-specific training data if the patient-specific feedback signal is available. Additionally, they can incorporate expert interventions, produce explanations for alarm predictions, and consider effects of medication on state changes to reduce false alert probability.

Objective

To enable prediction of clinical alerts via joint monitoring of multiple vital signs, while enabling timely adaptation of the model to particulars of a given patient.

Submitted by elamb on