Prevalence

Although recent data suggests childhood obesity prevalence has stabilized, an estimated 1 in 3 U.S. children are overweight or obese.1 Further, there is variation by racial and ethnic groups, location, age, and poverty2, resulting in a need for local data to support public health planning and evaluation efforts. Current methods for surveillance of childhood weight status rely on self-report from community-based surveys. However, surveys have long time intervals between data collection periods, are expensive, and are not often able to produce precise small-area estimates. EHRs have been increasingly proposed as an alternative or supplement to community surveys. Childhood weight and height is collected as a part of routine care, and leveraging these data from EHRs may provide rapid and locally precise estimates of childhood weight status. A concern for the use of EHRs is the potential for selection bias. EHRs represent only those seeking healthcare and may not generalize to the population. Additionally, the type of clinical visit (e.g., wellness vs. acute) may affect the prevalence estimates and the likelihood of collecting height and weight data in the EHR. Thus, in addition to EHRs being a convenience sample, there may be additional selection biases based on the type of visit and whether height and weight was measured and recorded. The current work sought to quantify the effect of visit type on childhood overweight and obesity prevalence and generate weights to adjust prevalence for potential EHR-related selection bias.

Objective: To discuss the use of electronic health records (EHRs) for estimation of overweight and obesity prevalence in children aged 2 to 19 years and to compare prevalence between the convenience sample obtained from EHRs to prevalence adjusted for potential selection bias.

Numerous studies have demonstrated a causal relationship between human papillomavirus (HPV) and cervical cancer1. By 2007 two vaccines targeting HPV were available in the United States. Both vaccines have shown close to 100% efficacy against HPV types 16 and 18, the cause of 70% of all cervical cancers2. It is hypothesized that with routine vaccination the prevalence of HPV and HPV-associated cancers should decline3. A need exists for surveillance with national coverage2. The purpose of this study is to present a method to estimate rate of change of high-risk HPV in the United States since 2004 in women using national reference laboratory data.

Objective

To establish and evaluate an HPV surveillance protocol and determine the rate of change of high-risk HPV in the United States since 2004 using archived reference laboratory data.

Brucellosis is one of the world'•s most widespread zoonosis. It is caused by gram-negative bacilli of the genus Brucella.It is a risk to those occupationally exposed to animals such as farmers, veterinarians, laboratorians and butchers and to the public through the consumption of contaminated unprocessed milk, milk products and meats.The epidemiology of Brucella infections involves complex mechanisms which vary according to the disease determinants. Previous studies in Kenya have reported a prevalence range of between 5% - 45% in livestock as well as over 20% in humans in selected regions1. Therefore, risk factors observed in a particular agro-ecological region cannot easily be extrapolated to another area with different ecological settings and husbandry practices. A strategy for brucellosis control would greatly benefit from detailed knowledge of local epidemiology. The available data on brucellosis is not adequate enough to inform an effective control process. Decision makers frequently apply different strategies according to the prevalence and epidemiology of the disease. People who interact with livestock on a regular basis are thought to be at an increased risk of contracting zoonoses including Brucellosis. Previous studies on Brucellosis have focused either on human or animal disease. The current study simultaneously investigated the linkage in sero-prevalence between humans and their animals within the same household at the same time.

Objective

We determined the sero-prevalence and risk factors for brucellosis in humans and their animals in Kajiado and Kiambu Counties of Kenya. We also examined the linkage between the sero-status of humans and that of their livestock.