Rabies PEP Administered v1

Query purpose: 

Created by the CDC National Syndromic Surveillance Program (NSSP) for use with emergency department data to develop queries for all National Notifiable Diseases defined by the National Notifiable Diseases Surveillance System (NNDSS). Please note that while the disease queries are developed using the NNDSS case definition as the basis for identifying patient visits of interest, the queried patient visits themselves may or may not represent a case patient in NNDSS and further public health investigation will most often be required. This query is intended to be a version 1 and may be further improved upon by the NSSP community of practice in the future. This query is intended to be narrow and capture visits with specific terms to support greater monitoring and actionable public health data. More complex and/or broader queries may exist that more broadly capture symptoms or travel-based terms.

How it was developed: 

1. The CDC team used the NNDSS case definition of Animal Rabies to identify diagnostic codes (International Classification of Diseases, 9th & 10th Revision (ICD-9-CM, ICD-10-CM), SNOMED Clinical Terms (CT)) and chief complaint free-text for syndrome development.
2. The codes and free text were then categorized as inclusion or exclusion terms. These terms were formatted for querying in ESSENCE.
3. Text analysis was conducted on the initial query to find additional inclusion or exclusion terms.
4. The query was cross-checked internally as NSSP and by CDC subject matter experts as needed.

How it works:

The Chief Complaint Discharge Diagnosis (CCDD) parsed field is used to query both the discharge diagnosis codes and chief complaint free text.

• Inclusion based on rabies related chief complaint free text terms:
  • The visit is included if it contains:
    1. Chief complaints related to the disease name – (“rabi[de]”, “rabbie”, “rabes”) OR
• Inclusion based on ICD-10 discharge diagnosis codes related to Rabies:
  • The visit is included if it contains:
    1. A discharge diagnosis code of Rabies (A82) OR
    2. A discharge diagnosis code of Contact with and (suspected) exposure to rabies (Z20.3) OR
    3. A discharge diagnosis code of Encounter for prophylactic rabies immune globin (Z29.14) OR
• Inclusion based on ICD-9 discharge diagnosis codes related to rabies:
  • The visit is included if it contains:
    1. A discharge diagnosis code of Rabies (071) OR
    2. A discharge diagnosis code of Contact with or exposure to rabies (V01.5) OR
    3. A discharge diagnosis code of Need for prophylactic vaccination and inoculation against rabies (V04.5) OR
• Inclusion based on SNOWMED discharge diagnosis codes related to rabies:
  • The visit is included if it contains:
    1. A discharge diagnosis code of Exposure to Rabies virus (444459008) OR
    2. A discharge diagnosis code of Administration of vaccine product containing only Rabies lyssavirus antigen (34631000) ANDNOT
• All of the above must exclude:
  • SNOMED discharge diagnosis codes related to adverse effects of Rabies vaccination:
    1. A discharge diagnosis code of Adverse reaction to component of vaccine product containing Rabies lyssavirus antigen (293118001) OR
    2. A discharge diagnosis code of Post rabies vaccination encephalitis (192714000)