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Non-parametric intensity bounds for the visualization of disease clusters

Description

Consider the most likely disease cluster produced by any given method, like SaTScan,  for the detection and inference of spatial clusters in a map divided into areas; if this cluster is found to be statistically significant, what could be said of the external areas adjacent to the cluster? Do we have enough information to exclude them from a health program of prevention? Do all the areas inside the cluster have the same importance from a practitioner perspective? How to access quantitatively the risk of those regions, given that the information we have (cases count) is also subject to variation in our statistical modeling? A few papers have tackled these questions recently; produces confidence intervals for the risk in every area, which are compared with the risks inside the most likely cluster. There exists a crescent demand of interactive software for the visualization of spatial clusters. A technique was developed to visualize relative risk and statistical significance simultaneously.

Objective

Given an aggregated-area map with disease cases data, we propose a criterion to measure the plausibility of each area in the map of being part of a possible localized anomaly.

Submitted by uysz on