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Hybrid Probabilistic Modeling and Automated Data Fusion for Biosurveillance Applications

Description

The increased threat of bioterrorism and naturally occurring diseases, such as pandemic influenza, continually forces public health authorities to review methods for evaluating data and reports. The objective of bio-surveillance is to automatically process large amounts of information in order to rapidly provide the user with a situational awareness. Most systems currently deployed in health departments use only statistical algorithms to filter data for decision-making. These algorithms are capable of high sensitivity, but this sensitivity comes at the cost of excessive false positives [2], especially when multiple syndrome groups and data types are processed.

Objective

An intelligent information fusion approach is proposed to identify and provide early alerting of naturally-occurring disease outbreaks, as well as bioterrorist attacks, while reducing false positives. The proposed system statistically preprocesses information from multiple sources and fuses it in a manner comparable with the domain expert's decision-making process. Currently, system users lower the false alarm rate by "explaining away" the statistical data anomalies with alternative hypotheses derived from external, non-syndromic knowledge. We seek to incorporate this heuristic decision-making into a probabilistic network that accepts the outputs of statistical algorithms in a hybrid model of domain knowledge and data inference.

Submitted by elamb on