Adaptation of GUARDIAN for Syndromic Surveillance During the NATO Summit

Special event driven syndromic surveillance is often initiated by public health departments with limited time for development of an automated surveillance framework, which can result in heavy reliance on frontline care providers and potentially miss early signs of emerging trends. To address timelines and reliability issues, automated surveillance system are required.


To develop and implement a framework for special event surveillance using GUARDIAN, as well as document lessons learned postevent regarding design challenges and usability.


January 24, 2018

A Novel Syndrome Definition Validation Approach for Rarely Occurring Diseases

Early detection of rarely occurring but potentially harmful diseases such as bio-threat agents (e.g., anthrax), chemical agents (e.g., sarin), and naturally occurring diseases (e.g., meningitis) is critical for rapid initiation of treatment, infection control measures, and emergency response plans. To facilitate clinicians’ ability to detect these diseases, various syndrome definitions have been developed. Due to the rarity of these diseases, standard statistical methodologies for validating syndrome definitions are not applicable.



May 30, 2018

Case Definition for Real-Time Surveillance of Influenza-like Illness

The Centers for Disease Control and Prevention case definition of influenza-like illness (ILI) as fever with cough and/or sore throat casts a wide net resulting in lower sensitivity which can have major implications on public health surveillance and response.



This study investigates additional signs and symptoms to further enhance the ILI case definition for real-time surveillance of influenza.

May 02, 2019

Disease Profile Development Methodology for Syndromic Surveillance of Biological Threat Agents

Detection of biological threat agents (BTAs) is critical to the rapid initiation of treatment, infection control measures, and public health emergency response plans. Due to the rarity of BTAs, standard methodology for developing syndrome definitions and measuring their validity is lacking.



May 02, 2019


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