Monitoring of long-term infectious disease mortality trends is of great value to national public health systems both in estimation of the efficacy of preventive programs, and in development of the new strategies of preventive measures. In the developed countries, there are a number of studies with long-term time series of infectious disease mortality analysis in epidemiological and historical aspects. Our research was based on the work by Armstrong GL, Conn LA and Pinner RW, 1999. Literature review revealed that such analysis has been never carried out in Ukraine up to now.