Mobley Evan

In 2016, there were approximately 63,000 deaths nationally due to drug overdose. This trend continues to increase with the provisional number of US deaths for 2017 being approximately 72,000 (1). This increase in overdose deaths is fueled largely by the opioid class of drugs. The opioid epidemic began in the 1990s with a steady rise in prescription opioid overdoses. However, after 2010 a rise in heroin overdose deaths also began to occur. In addition to the heroin deaths increasing, there was a sharp rise in overdose deaths due to synthetic opioids including illicitly manufactured fentanyl beginning in 2013 (2). In Missouri, ER visits follow similar trends with heroin overdose visits greatly increasing after 2011. While PDMPs help function as data sources that provide information on the licit drug supply, they cannot give much knowledge on the illicit supply. Because of this, drug seizure data from law enforcement can provide a much-needed tool in understanding the supply of illicit substances and their impact on a county™'s morbidity.

Objective: To evaluate the relationship between heroin and non-heroin opioid seizures reported by law enforcement and the number of ER visits due to heroin and non-heroin opioid poisoning in selected counties in Missouri.

In 2017, 951 Missouri residents died from an opioid overdose, a record number for the state.1 This continues the trend from 2016, which saw an increase of over 30% in opioid overdose deaths compared to 2015. The Missouri Department of Health and Senior Services (MDHSS) manages several public health surveillance data sources that can be used to inform about the opioid epidemic. Opioid overdose deaths are identified through death certificates which are collected through the vital records system. MDHSS also manages the Patient Abstract System (PAS), which contains ED and inpatient hospitalization data from approximately 132 non-federal Missouri hospitals. PAS contains about 130 variables, which include demographic data, diagnoses codes, procedures codes, and other visit information. Records can have up to 23 diagnosis fields, which are coded using ICD-10-CM (International Classification of Diseases, Clinically Modified). The first diagnosis field is the primary reason for a visit.

Objective: Link emergency department (ED) with death certificate mortality data in order to examine the prior medical history of opioid overdose victims leading up to their death.

Neonatal Abstinence Syndrome (NAS) rates have tripled for Missouri residents in the past three years. NAS is a condition infants suffer soon after birth due to withdrawal after becoming opioid-dependent in the womb. NAS has significant immediate health concerns and can have long term effects on child development and quality of life. The Missouri Department of Health and Senior Services (MODHSS) maintains the Patient Abstract System (PAS), a database of inpatient, emergency room, and outpatient records collected from non-federal hospitals and ambulatory surgical centers throughout the state. PAS records contain extensive information about the visit, patient, and diagnosis. When examining 2015 annual PAS data for NAS-associated discharges, Missouri analysts noticed a greater than 50% increase in discharges, even larger than anticipated in light of the opioid epidemic. Provisional 2016 data produced similar high rates, dispelling the notion that the trend was a transitional problem. In fact, provisional 2016 rates are 115% higher than NAS rates in 2015. In contrast, percentage change of opioid misuse emergency department visits (as defined by MODHSS) for Missouri women age 18-44 was +13% in 2015 and -12% in 2016.

Objective:

In this analysis we examine Missouri NAS discharge rates with special focus on the ICD-9-CM/ICD-10-CM transition and changes in code descriptions.

Like many other states in the U.S., Missouri has experienced large increases in opioid abuse resulting in hundreds dying each year and thousands of ED visits due to overdose. Missouri has two major urban areas, St. Louis and Kansas City and a few smaller cities, while the remainder of the state is more rural in nature. The opioid epidemic has impacted all areas in the state but the magnitude of that impact varies as well as the type of opioid used. Missouri Department of Health and Senior Services (MODHSS) maintains the Patient Abstract System (PAS) which contains data from hospitals and ambulatory surgical centers throughout the state. PAS includes data from ED visits including information on diagnoses, patient demographics, and other information about the visit. MODHSS also participates in the Enhanced State Surveillance of Opioid-involved Morbidity and Mortality project (ESOOS). One major aspect of this surveillance project is the collection of data on non-fatal opioid overdoses from ED visits. Through this collection of data, MODHSS analyzed opioid overdose visits throughout the state, how rates compare across urban and rural areas, and how those rates have changed over time.

Objective:

Compare rate changes over time for Emergency Department (ED) visits due to opioid overdose in urban versus rural areas of the state of Missouri.