A bootstrapping method to improve cohort identification

The research reported in this paper is part of a larger effort to achieve better signal-to-noise ratio, hence accuracy, in pharmacovigilance applications. The relatively low frequency of occurrence of adverse drug reactions leads to weak causal relations between the reaction and any measured signal. We hypothesize that by grouping related signals, we can enhance detection rate and suppress false alarm rate.



June 07, 2019

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