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Analytic Biosurveillance Methods for Resource-Limited Settings

Description

Biosurveillance in resource-limited settings is essential because of both enhanced risk of diseases rarely seen elsewhere (e.g. cholera) and pandemic threats (e.g. avian influenza). However, access to care and laboratory test capability are typically inadequate in such areas, amplifying the importance of syndromic surveillance. Such surveillance in turn may be a challenge because of insufficient data history and systematic or seasonal behavior. The Suite for Automated Global Electronic bioSurveillance (SAGES) is a collection of modular, freely-available software tools to enable electronic surveillance in these settings. These tools require statistical alerting methods appropriate for SAGES data, and development of such methods is the subject of this effort. We evaluated alerting methods for two main uses: weekly surveillance for seasonal outbreaks such as dengue fever and influenza, and daily syndromic data for settings where monitoring and response on a daily basis are practical. The latter situation has the added complication that day-of-week clinical visit patterns differ widely, (e.g. clinic closure on Sundays and Thursdays) and may evolve over time.

Objective

The authors develop open-source temporal alerting algorithms for data environments characteristic of resource-limited geographic settings and recommend appropriate usage of each.

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